Location: Mayo Clinic, Phillips Hall, Siebens Building
Lecturer: Stephen J. Russell, MD, PhD
Dr. Russell’s research is focused on developing
engineered viruses for the treatment of
disseminated malignancies and demonstrating
their efficacy in clinical trials. Research themes in
his laboratory include engineering viral membrane
glycoproteins, targeting cell-to-cell fusion,
targeting virus entry, using cellular microRNAs to
reprogram virus tropism, modulating and
exploiting virus-tumor-immune system
interactions, performing pharmacokinetic and
pharmacodynamic studies of virus-based
therapies, noninvasive monitoring and imaging of
viral gene expression in vivo, and studying
radiovirotherapy.
Dr. Russell will discuss how viruses are being
harvested for the advancement of 21st century
medicine. Insights into virus engineering will be
provided to give attendees a deeper understanding
of the mechanics of gene therapy, regenerative
medicine, and oncolytic virotherapy.